Bryan Johnson’s experiment consisted of 60 hour-and-a-half sessions of HBOT over the course of 90 days
A ‘biohacker’ who claims to spend $2 million every year to ‘live forever’ has revealed his biggest concerns he had while undertaking oxygen therapy treatment.
Bryan Johnson recently completed an experiment, which consisted of 60 hour-and-a-half sessions of completing hyperbaric oxygen therapy (HBOT), over the course of 90 days.
For those of us not in the know, it is a medical treatment in which patients breathe pure oxygen in a special chamber with increased air pressure, which allows the body to absorb significantly more oxygen.
Such extra oxygen can be beneficial in treating a variety of conditions, including wounds, infections and a lot of other sickness involved with that area of the body.
On his mission to stop aging, the 47-year-old Utah native uploaded his findings to his YouTube channel – where he raised his biggest concerns with the treatment.

Bryan Johnson donning the oxygen mask for the HBOT treatment (Bryan Johnson/YouTube)
Speaking to his followers on the platform, he explained exactly what those fears are: “When you first start doing HBOT it definitely is a unique experience; one you’re in a highly pressurized chamber and it makes you wonder what if something goes wrong?
“I live in California, there’s a lot of earthquakes and I wondered, ‘if there’s an earthquake if I had to do something fast how fast can I move?’, and so the fastest depressurization time from two atmospheres is around two minutes.
“A lot of my friends couldn’t even get inside the chamber, they’re too claustrophobic. Also though, when you put on the mask sometimes it can feel a little restricting – where you breathe in there’s some resistance when you are doing the therapy.”

Johnson’s experiment consisted of 60 hour-and-a-half sessions of HBOT over the course of 90 days (YouTube/Bryan-Johnson)
Johnson added: “So there’s problems there HBOT really tries you from claustrophobia breathing duration of time and also if you don’t have anything to do you’re kind of left with your thoughts.”
Johnson revealed he saw a 300 percent growth in blood vessels and a 1000 precent increase in akkermansia, which is linked to improved gut and metabolic health.
A marker for the chances of developing Alzheimer’s also declined by 28 percent as a result of Johnson using the oxygen therapy for the past three months.Playhttps://www.youtube-nocookie.com/embed/pfSFnFWb8X4?autoplay=1&playsinline=1
The procedure also ‘transformed’ Johnson’s skin across his whole body, while his UV skin damage improved by around 10 percent.
Telomeres, which are located at the ends of chromosomes, are a significant indication of ‘biology age and health’, which were also measured during the experiment.
A marker for the chances of developing Alzheimer’s also declined by 28 percent as a result of Johnson using the oxygen therapy for the past three months.
The procedure also ‘transformed’ Johnson’s skin across his whole body, while his UV skin damage improved by around 10 percent.
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Telomeres, which are located at the ends of chromosomes, are a significant indication of ‘biology age and health’, which were also measured during the experiment.Featured Image Credit: YouTube/Bryan Johnson
Topics: Bryan Johnson, Health, YouTube, Science

Updated 08:14 3 Jun 2025 GMT+1Published 15:41 2 Jun 2025 GMT+1
Biohacker who spends $2,000,000 to ‘live forever’ reveals insane results after using oxygen therapy for 90 days
Bryan Johnson is hoping to ‘live forever’ with the methods he is undertaking
A self-proclaimed biohacker who has spent a whopping $2 million to ‘live forever’ has revealed some insane results after using oxygen therapy for the past 90 days.
Bryan Johnson is taking part in a lengthy and intense experimental medical program in the hope of ‘reversing aging’, and it’s safe to say it’s been a resounding success so far.
Whether it be following a strict diet or using his son’s blood, Johnson is doing everything possible to remain as young as possible.
While he may be in his late 40s, the biohacker has previously said his crazy experiment helped him achieve the ‘heart of 37-year-old’ and the ‘lung capacity of an 18-year-old’.

Bryan Johnson is hoping to ‘live forever’ (Kyle Grillot/Bloomberg via Getty Images)
Recently, Johnson embarked on 90 days of using hyperbaric oxygen therapy, a form of medical treatment where a patient breathes pure oxygen in a special chamber with increased air pressure, which allows the body to absorb significantly more oxygen.
Such extra oxygen can be beneficial in treating a variety of conditions, including wounds, infections and a lot of other sickness involved with that area of the body.
Johnson completed 60 sessions over the period of 90 days, all lasting 90 minutes in duration.
In a video uploaded to his YouTube channel, Johnson revealed he saw a 300 percent growth in blood vessels and a 1000 precent increase in akkermansia, which is linked to improved gut and metabolic health.
A marker for the chances of developing Alzheimer’s also declined by 28 percent as a result of Johnson using the oxygen therapy for the past three months.
The procedure also ‘transformed’ Johnson’s skin across his whole body, while his UV skin damage improved by around 10 percent.
Telomeres, which are located at the ends of chromosomes, are a significant indication of ‘biology age and health’, which were also measured during the experiment.Play
Johnson was found to have that of a ten-year-old, showing the incredible impact the oxygen therapy has had on his mission to ‘live forever’.
Some of the wild things Johnson has done to stay youthful has seen him receive much criticism online, including sharing his and his son’s ‘erection data’.
The data included the pair’s sleep efficiency, average erection quality, number of erection episodes and total duration.
Johnson achieved a better average erection quality with 94, while his son Talmage received a slightly lower 90 score.
The biohacker also had much better sleep efficiency, but had one less erection episode compared to Talmage.Featured Image Credit: YouTube/Bryan Johnson
Topics: Bryan Johnson, Health, Technology, Weird, YouTube

Published 12:38 21 May 2025 GMT+1
Biohacker who wants to ‘live forever’ claims if men aren’t having these specific erections they’re ‘70% more likely to die’
Bryan Johnson has been on an unbelievable health journey he hopes will make him ‘live forever’
A self-proclaimed biohacker who wants to ‘live forever’ has claimed on a new podcast how men are ‘70% more likely to die’ if they aren’t having a specific type of erection.
Bryan Johnson is taking part in a lengthy and intense experimental medical program in the hope of ‘reversing aging’, and it’s safe to say it’s been a resounding success so far.
Whether it be following a strict diet, or using his son’s blood, Johnson is doing anything possible to remain as young as possible.
While he may be in his late 40s, the biohacker has previously said his crazy experiment helped him achieve the ‘heart of 37-year-old’ and the ‘lung capacity of an 18-year-old’.
And speaking on The Louis Theroux Podcast, the biohacker discussed a whole bunch of topics, including erections – because of course he did.

Bryan Johnson has been speaking about erections on a recent podcast (Kyle Grillot/Bloomberg via Getty Images)
Making a remarkable claim, Johnson said: “If you’re not having nighttime boners, you’re 70 percent more likely to die.”
Speaking further about how erections while you are sleeping can be monitored, the biohacker added: “You need some kind of measurement as they happen during sleep cycles so you’re oblivious to a lot of it.
“You need technology, so you need a little cube and you put it on the penis, it sits at the base, and as your penis gorges throughout the night, it measures the duration and the strength of the eruption.”
Speaking further on The Ranveer Show podcast earlier this year, Johnson added: “Men who do not have nighttime erections are 70 percent more likely to die prematurely. It predicts death.
“On average, a 20-year-old male should have between 3 and 5 erection episodes per night, yeah, like, 145 minutes of erections, and that’s healthy. By the time you’re 75, that reduces to about 50 minutes, so dramatically declines with age. Nighttime erections are, like, a really important health marker.”

Bryan Johnson is planning to ‘live forever’ (Instagram/@bryanjohnson__)
Dr Srikanth V, a specialized urologist, discussed the potential link between nighttime erections and premature death.
“While the absence of nighttime erections is associated with certain health risks, the claim that it directly predicts premature death is an oversimplification,” the doctor told the Indian Express.
“Several studies suggest that erectile dysfunction — particularly when caused by vascular or metabolic issues — is linked to a higher risk of cardiovascular disease (CVD) and all-cause mortality.
“Since nighttime erections are largely driven by healthy vascular function and neural pathways, their absence may be a red flag for conditions such as atherosclerosis, diabetes, and hormonal imbalances, which themselves are associated with increased mortality risk.”Featured Image Credit: Getty Images/Bloomberg
Topics: Bryan Johnson, Health

Published 10:32 15 Jan 2025 GMT
Biohacker who spends $2,000,000 a year to ‘live forever’ reveals concerning reason he has stopped taking longevity drug
Bryan Johnson and his team found the drug did ‘not justify’ what was happening to him
Biohacker Bryan Johnson has explained why he’s ditched a purported anti-ageing drug despite his ongoing efforts to try and ‘live forever’.
Johnson, who is 47 years old but claims to have the heart health of a 37-year-old, spends as much as $2 million a year on research and trials to try and reduce his biological age.
His efforts have included ‘editing’ his DNA and sharing blood with his family members, and he’s also described taking a cocktail of supplements and drugs to ward off ageing.

Bryan Johnson says his organs are younger than his actual age (Kyle Grillot/Bloomberg via Getty Images)
Among those drugs was rapamycin; a drug typically used to treat conditions such as cancer or lung diseases, but which has also been studied for its anti-ageing properties.
It was this latter use that Johnson was interested in as he took part in ‘almost 5 years of experimentation with this molecule for its longevity potential’.
However, in a post on Twitter shared in recent weeks, Johnson announced that he stopped taking rapamycin in September 2024.
The biohacker told his followers he’d been testing the drug in various different ways, switching up dosages and schedules to ‘optimize rejuvenation and limit side effects’.
But while pre-clinical trials revealed ‘immense potential’, Johnson revealed a concerning finding: the drug could actually have been speeding up the ageing process due to its side-effects.
Johnson listed the symptoms he’d experienced from taking the drug, including ‘intermittent skin/soft tissue infections, lipid abnormalities, glucose elevations, and increased resting heart rate’.

Johnson said the drug was not worth the side-effects (David Paul Morris/Bloomberg via Getty Images)
Research cited by the National Library of Medicine has indicated a link between a higher resting heart rate and increased risk of cardiovascular disease, meaning the symptom experienced by Johnson could have detrimental effects in the long term.
He went on to site research published in October that indicated rapamycin was ‘one of a handful of supposed longevity interventions to cause an increase/acceleration of aging in humans across 16 epigenetic aging clocks’.
With that in mind, Johnson explained: “My team and I came to the conclusion that the benefits of lifelong dosing of Rapamycin do not justify the hefty side-effects.
“With no other underlying causes identified, we suspected Rapamycin, and since dosage adjustments had no effect, we decided to discontinue it entirely.”
“Longevity research around these experimental compounds is constantly evolving, necessitating ongoing, close observation of the research and my biomarkers which my team and I do constantly,” he added.
Though Johnson has decided to stop using rapamycin, his mission to reverse ageing is ongoing, and he continues to shares insights and updates with his followers.Featured Image Credit: YouTube/Bryan Johnson
Topics: Health, Science, Bryan Johnson

Published 10:49 29 Jan 2025 GMT
Biohacker who spends $2,000,000 a year to ‘live forever’ reveals bizarre new treatment plan after ‘no longer injecting son’s blood’
Bryan Johnson is planning to reveal the outcome of his new treatment plan after ‘rigorous testing’
Biohacker Bryan Johnson has revealed he’s ‘upgraded’ his approach to treatment after giving up on ‘injecting [his] son’s blood’.
Johnson has made a name for himself thanks to his efforts to avoid ageing at all costs – literally.
The ‘biohacker’ has spent millions of dollars on research to keep his body younger than his biological age, and has previously spoken about having the heart of a 37-year-old, the skin of a 28-year-old, and the lung capacity of an 18-year-old.
For context, Johnson was born 47 years ago.
Don’t Die: The Man Who Wants To Live Forever trailer
Credit: Netflix
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As part of his mission, Johnson announced in 2023 that he’d come together with his then-17-year-old son and his 70-year-old father to take part in what he described as ‘the world’s first multigenerational plasma exchange’.
The process saw Johnson have a litre of his blood removed and separated the plasma. He then had the same amount of his son’s plasma infused into his veins.
Johnson took on the exchange as as a possible treatment for cognitive decline, but on January 28, he shared an update to say he was taking things in a new direction.
The biohacker shared an image of himself holding a large bag of yellow-orange liquid, and wrote: “I am no longer injecting my son’s blood.”
He announced he’d instead ‘upgraded’ to ‘total plasma exchange’.
Johnson went on to detail the ‘steps’, saying:
“1. Take out all blood from body
“2. Separate plasma from blood
“3. Replace plasma with 5% albumin & IVIG”
He concluded his post: “Here’s my bag of plasma. Who wants it?”

Johnson asked followers who wanted his plasma (X/@bryan_johnson)
Cleveland Clinic explains that albumin is protein in your blood plasma. If you have a low level of albumin, it could be the result of kidney disease, liver disease, inflammation, or infections, while high levels are often the result of dehydration or severe diarrhea.
IVIG stands for intravenous immunoglobulin, and is a product of the blood which is used to treat conditions by replacing antibodies in the body.
Explaining the reason for his new approach, Johnson claimed in a thread that total plasma exchange has ‘great effects in removing toxins, waste products, old misfolded and glycated proteins and immune complexes’.

Johnson has spent millions to avoid ageing (David Paul Morris/Bloomberg via Getty Images)
The biohacker claimed the process has also shown ‘measurable effects in delaying and reversing age-related disease including dementia, as well as the capacity to reduce biological age based on various parameters, including blood proteomics and biological aging clocks’.
Johnson is set to put the theory through some ‘rigorous’ testing, planning: “Bi-weekly protocol, 2x [Total Plasma Exchange] with 5% albumin, spaced by 4 days [and] 20g of IVIG following each TPE session.”
He explained: “By implementing this protocol along with thorough measurement, my team and I aim to figure out what works best when it comes to the use of TPE as a rejuvenation and longevity therapy.”
Johnson is set to share updates on the process after his upcoming second bi-weekly session.Featured Image Credit: X/Bryan Johnson
Topics: Bryan Johnson, Health, Science